In an article “Cardiovascular Disease Resulting from a Diet and Lifestyle at odds with our Paleolithic Genome” published in Mayo Clinic Proc. Jan 2009 by James O’Keefe MD and Loren Codain PhD we see why it is so essential to restore metabolic balance in clients with a Keto/Paleo type diet, intermittent fasting, exercise, sleep and outdoor activities to emulate the HunterGatherer lifestyles of our ancestors.
“Humans evolved during the Paleolithic period, from approximately 2.6 million years ago to 10,000 years ago. Although the human genome has remained largely unchanged (DNA evidence documents relatively little change in the genome during the past 10,000 years), our diet and lifestyle have become progressively more divergent from those of our ancient ancestors. These maladaptive changes began approximately 10,000 years ago with the advent of the agricultural revolution and have been accelerating in recent decades. Socially, we are a people of the 21st Century, but genetically we remain citizens of the Paleolithic era.
Today most of us dwell in mechanized urban settings, leading largely sedentary lives and eating a highly processed synthetic diet. As a result, two thirds of Americans are overweight or obese. The lifetime incidence of hypertension is an astounding 90%, and the metabolic syndrome is present in up to 40% of middle-aged American adults. Cardiovascular disease remains the number 1 cause of death, accounting for 41% of all fatalities, and the prevalence of heart disease in the United States is projected to double during the next 50 years.”